Untertitel:: Applications in Drug Discovery
Verlag:: WILEY-VCH
Erschienen:: 27.06.2007
Seitenanzahl:: 460
EAN:: 9783527610914
Sprache:: Englisch
Format:: PDF
Schutz:: Adobe-DRM
Downloadzeit:: Maximaler Downloadzeitraum: 24 Monate

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Mass Spectrometry in Medicinal Chemistry

This first overview of mass spectrometry-based pharmaceutical analysis is the key to improved high-throughput drug screening, rational drug design and analysis of multiple ligand-target interactions. The ready reference opens with a general introduction to the use of mass spectrometry in pharmaceutical screening, followed by a detailed description of recently developed analytical systems for use in the pharmaceutical laboratory.<br> Applications range from simple binding assays to complex screens of biological activity and systems containing multiple targets or ligands -- all highly relevant techniques in the early stages in drug discovery, from target characterization to hit and lead finding.