Untertitel:: In the 21st Century
Verlag:: HUMANA PRESS
Erschienen:: 28.10.2007
Seitenanzahl:: 416
ISBN:: 1592599311
EAN:: 9781592599318
Sprache:: Englisch
Format:: PDF
Schutz:: Dig. Wass.
Downloadzeit:: Maximaler Downloadzeitraum: 24 Monate

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The Adrenergic Receptors

An authoritative review of the current state-of-the-art understanding of the structure and function of the adrenergic receptor subtypes, as well as of the role played by these receptors in physiological and pathophysiological settings. Topics range from structure-function studies and the imaging of adrenergic receptors to the use of genetically altered mouse models and pharmacogenomics. Highlights include a survey of the knockout and overexpressed mouse models, a review of the new ways that adrenergic receptors can signal, and the effects of polymorphisms on clinical outcomes and on potential gene therapy applications. The side-by-side comparison of all the adrenergic receptors (a1, a2, and b) provides the reader with an excellent survey of the field, including the rationale for designing better drugs to control blood pressure and heart function.